Quickly progressive glomerulonephritis associated with lupus nephritis in a middle age patient

Authors

  • Yoandri Bandera Ramos Hospital General Docente “Dr. Juan Bruno Zayas Alfonso”, Santiago de Cuba
  • Pablo Yulior Ge Martínez Hospital General Docente “Dr. Juan Bruno Zayas Alfonso”, Santiago de Cuba
  • Yunia Correa Acuña Hospital General Docente “Dr. Juan Bruno Zayas Alfonso”, Santiago de Cuba

Keywords:

progressive glomerulonephritis, lupus nephritis, systemic erythematous lupus, renal failure, Nephrology Service.

Abstract

The case report of a 47 years patient is described with a history of lymphoproliferative syndrome who was admitted at the Hematology room of "Dr. Juan Bruno Zayas Alfonso" Teaching General Hospital in Santiago de Cuba, and then she was transferred to the Nephrology Service due to a polyarticular pain, fever, edemas, decrease of diuresis and progressive increase of the plasmatic creatinine.  The clinical pattern and the lab tests allowed to diagnose a quickly progressive glomerulonephritis as consequence of a lupus nephritis class IV.  The patient was treated with prednisone and cyclophosphamide, and she showed a satisfactory clinical course without the necessity of using hemodyalisis treatment.

Downloads

Download data is not yet available.

Author Biography

Yoandri Bandera Ramos, Hospital General Docente “Dr. Juan Bruno Zayas Alfonso”, Santiago de Cuba

Medico Especialista I grado Nefrologia.

References

1. Aguiar A, Álvarez P, Wasiuchnik VP, Abib A, Ciliberti E, Moretti L, et al. Glomerulonefritis rápidamente progresiva en ancianos. Medicina (B. Aires). 2013; 73(2): 148-52.

2. Carreño A, Rivera F, Egido J. Glomerulonefritis extracapilares. En: Avendaño L. Nefrología Clínica. Madrid: Editorial Panamericana; 2008. p. 368-74.

3. Goch DV, Verna M. Nefropatía lúpica: revisión. Rev Posgrado Vía Cátedra Med. 2003; 125(3): 7-9.

4. Buttgereit F, Burmester GR, Lipworth BJ. Optimised glucocorticoid therapy: the sharpening of an old spear. Lancet. 2005; 365(9461): 801-3.

5. Ruiz Irastorza G, Espinosa G, Frutos MA, Jiménez Alonso J, Praga M, Pallarés L, et al. Diagnóstico y tratamiento de la nefritis lúpica. Documento de consenso del Grupo de Enfermedades Autoinmunes Sistémicas (GEAS) de la Sociedad Española de Medicina Interna (SEMI) y de la Sociedad Española de Nefrología (S.E.N.). Nefrología (Madr.). 2012 [citado 17 Sep 2016]; 32(Suppl. 1). Disponible en: http://scielo.isciii.es/scielo.php?pid=S0211-69952012000300001&script=sci_arttext&tlng=pt

6. Houssiau F A, Vasconcelos C, D'Cruz D, Sebastiani GD, Garrido Ed Ede R, Danieli MG, et al. Immunosuppressive therapy in lupus nephritis: the Euro-Lupus Nephritis Trial, a randomized trial of low-dose versus high-dose intravenous cyclophosphamide. Arthritis Rheum. 2002; 46(8): 2121-31.

7. Yee C, Gordon C, Dostal C, Petera P, Dadoniene J, Griffiths B, et al. EULAR randomised controlled trial of pulse cyclophosphamide and methylprednisolone versus continous cyclophosphamide and prednisolone followed by azathioprine and prednisolone in lupus nephritis. Ann Rheum Dis. 2004; 63(5): 525-9.

8. Illei GG, Austin HA, Crane M, et al. Combination therapy with pulse cyclophosphamide plus pulse methylprednisolone improves long-term renal outcome without adding toxicity in patients with lupus nephritis. Ann Intern Med. 2001; 135(4): 248-57.

9. Appel GB, Contreras G, Dooley MA, Ginzler EM, Isenberg D, Jayne D, et al. Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis. J Am Soc Nephrol. 2009; 20(5): 1103-12.

10. Matsumura R, Umemiya K, Sugiyama T, Sueishi M, Umibe T, Ichikawa K, et al. Anti-tumor necrosis factor therapy in patients with difficult-to-treat lupus nephritis: a prospective series of nine patients. Clin Exp Rheumatol. 2009; 27(3): 416-21.

Published

2017-08-09

How to Cite

1.
Bandera Ramos Y, Ge Martínez PY, Correa Acuña Y. Quickly progressive glomerulonephritis associated with lupus nephritis in a middle age patient. MEDISAN [Internet]. 2017 Aug. 9 [cited 2025 Jun. 3];21(8). Available from: https://medisan.sld.cu/index.php/san/article/view/1015

Issue

Section

Case Reports