Predictive factors of severity in pregnant women with suspected Oropouche fever belonging to communities in Santiago

Abstract

Introduction: In recent decades, there has been an increasingly noticeable increase in the number of epidemics caused by arboviruses.Objective: To Identify predictive factors associated with severity status in pregnant women with suspected Oropouche fever.Methods: An observational, analytical case-control study was carried out. A sample of 75 pregnant women in severity status (cases) and 150 without this condition (controls) was selected. A bivariate analysis was performed to look for association between each predictive factor.Results: Frequent vomiting (60.0%) and elevated transaminases (54.7 %) were the most prevalent findings in this series. Although less frequent, the presence of 3 miscarriages (10.0 %), 2 threatened pregnancies (6.7 %), and one late fetal death (3.3 %) is noteworthy. The main predictive factors observed in this series were inadequate BMI at blood glucose uptake (OR: 16.09; 95% CI: 7.14–36.23) and elevated transaminases (OR: 13.20; 95 % CI: 5.66–30.70). On the other hand, abundant diarrhea [(OR: 5.53 (2.16 – 14.16)], the first trimester of pregnancy [(OR: 3.00 (1.69 – 5.32)] and frequent vomiting [(OR: 2.62); (95 % CI: (1.48 - 4.70)] are also associated with the meaning given by the dependent variable.Conclusions: It is concluded that Oropouche virus infection in pregnant women manifests in varied ways and does not differ substantially from what has been reported in the specialized literature. Nutritional status and digestive disorders act as factors that increase the causality of the severity status in the studied population.