Clinical laboratory studies for the detection of chronic renal disease in population risk groups

Authors

  • Denia Martínez Pérez Hospital Provincial Docente Clinicoquirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba.
  • Lutgarda Pérez de Alejo Rodríguez Hospital Provincial Docente Clinicoquirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, Cuba.
  • Carmen Xiomara Moré Chang Instituto Superior de Ciencias Médicas de Villa Clara “Dr. Serafín Ruiz de Zarate Ruiz”, Santa Clara, Villa Clara, Cuba.
  • Ricardo Rodríguez Viera Hospital General Docente “Mártires del 9 de abril”, Sagua la Grande, Villa Clara, Cuba.
  • Juan Carlos Dupuy Nuñez Dirección Provincial de Salud, Villa Clara, Cuba.

Keywords:

chronic renal disease, renal damage markers, clinical laboratory studies, population studies

Abstract

A descriptive and cross-sectional study (intentional probabilistic sampling) of 114 selected patients, previous informed consent, as populational risk group non classified due to renal chronic disease, belonging to a doctor´s office from "Chiqui Gómez Lubián" Teaching Community Polyclinic in Santa Clara, Villa Clara was carried out from January to December, 2013 in whom an inquiry, physical exam and laboratory tests (microalbuminuria, Addis count and creatinine in blood,  that allowed to estimate the glomerular filtrate) were carried out, with the objective of identifying the disorder and its characteristics.  The illness was diagnosed in a fourth of the total, fundamentally in stage II, and a high association frequency of positive microalbuminuria and Addis pathological count was observed; likewise, the ages of 65 years and more prevailed, which were associated with the most advanced stages.  Hypertension and diabetes mellitus were the most frequent risk factors, while the clinical symptoms (nocturia and foamy urines) and the sign of hypertension was present with more frequency in stage III (late).  It could be concluded that for initial stages it was very important the indication of microalbuminuria and Addis count for the initial stages and in the advanced stages classics clinical symptoms of nephropathy were observed.

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References

1. Arce Bustabad S, Pérez Oliva J. Transplante renal y enfermedad renal crónica. Sistema de leyes integradoras. En: Almaguer López M. Primera Ley. La Habana: Editorial Ciencias Médicas; 2009. p 24-29.

2. Pérez-Oliva Díaz JF, Portal Miranda JA. Enfermedad renal crónica: estrategia nacional para enfrentar este importante problema de salud. Rev Haban Cienc Méd. 2010 [citado 26 Abr 2013]; 9(2). Disponible en: http://scielo.sld.cu/scielo.php?pid=S1729-519X2010000200001&script=sci_arttext&tlng=en

3. Chronic Kidney Disease Prognosis Consortium, Matsushita K, van der Velde M, Astor BC, Woodward M, Levey AS. Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet. 2010; 375(9731): 2073-81.

4. Campos Gutiérrez B, Lou Arnal A, Gimeno Orna JA, Gracia García O, Cuberes Izquierdo M, Turón Alcaine JM, et al. La enfermedad renal que se oculta tras los ingresos: una oportunidad de mejora. Nefrología. 2011; 31(1):70-5. Disponible en: http://scielo.isciii.es/pdf/nefrologia/v31n1/original4.pdf

5. Iseki K. Chronic kidney disease in Japan. Intern Med. 2008; 47(8):681-9.

6. Bello AK, Peters J, Wight J, de Zeeuw D, El Nahas M, European kidney Institute. A population-based screening for microalbuminuria among relatives of CKD patients: the kidney evaluation and awareness program in Sheffield (KEAPS). Am J Kidney Dis. 2008; 52(3): 434-43.

7. Finkelstein FO, Finkelstein SH. Reassessment of the care of the patient with chronic kidney disease. Kidney Int. 2010; 77(11): 945-7.

8. D'achiardi Rey R, Vargas JG, Echeverri JE, Moreno M, Quiroz G. Factores de riesgo de enfermedad renal crónica. Rev Med. 2011 [citado 24 May 2012]; 19(2). Disponible en: http://www.scielo.org.co/pdf/med/v19n2/v19n2a09.pdf

9. Lou Arnal LM, Campos B. Estimación de filtrado glomerular en atención primaria: prevalencia de enfermedad renal crónica y repercusión sobre la derivación a Nefrología. Nefrología. 2008; 28(3): 329-32.

10. De Francisco AL, De la Cruz JJ, Cases A, De la Figuera M, Egocheaga MI, Górriz JI, et al. Prevalencia de insuficiencia renal en centros de atención primaria en España: estudio EROCAP. Nefrología. 2007; 27(3): 300-12.

11. Qui-Li Z, Rothenbacher D. Prevalence of chronic kidney disease in population-based studies: systematic review. BMC Public Health. 2008; 8: 117. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377260/pdf/1471-2458-8-117.pdf

12. Rong X, Lu-Xia Z, Pu-Hong Z, Fang W, Li Z, Hai-Yan W. Gender differences in age-related decline in glomerular filtration rates in healthy people and chronic kidney disease patients. BMC Nephrol. 2011; 11: 20. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936369/pdf/1471-2369-11-20.pdf

13. Hanratty R, Chonchol M, Dickinson M, Beaty BL, Estacio RO, Mackenzie TD, et al. Incident chronic kidney disease and the rate of kidney function decline in individuals with hypertension. Nephrol Dial Transplant. 2012; 25(3): 801–7.

14. Grupo de Acción Estratégica de la S.E.N, Martínez Castelao A, Martín de Francisco AL, Górriz JL, Alcázar R, Orte L. Estrategias en salud renal: un proyecto de la Sociedad Española de Nefrología. Nefrología. 2009; 29(3): 185-92.

15. Janus N, Launay-vacher V, Byloos E, Machiels JP, Duck L, Kerger J, et al. Cancer and renal insufficiency results of the BIRMA study. Br J Cancer. 2010; 103(12): 1815-21.

16. Tong A, Sainsbury P, Carter SM, Hall B, Harris DC, Walker RG, et al. Patients' priorities for health research: focus group study of patients with chronic kidney disease. Nephrol Dial Transplant. 2008; 23(10): 3206–14.

17. Singh NP, Ingle GK, Saini VK, Jami A, Beniwal P, Lal M, et al. Prevalence of low glomerular filtration rate, proteinuria and associated risk factors in North India using cockcroft-gault and modification of diet in renal disease equation: an observational, cross-sectional study. BMC Nephrol. 2009; 10:4.

18. Martín de Francisco AL, Piñera C, Gago M, Ruiz J, Robledo C, Arias M. Epidemiología de la enfermedad renal crónica en pacientes no nefrológicos. Nefrología. 2009; 29(Sup. Ext. 5): 101-5.

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Published

2016-01-14

How to Cite

1.
Martínez Pérez D, de Alejo Rodríguez LP, Moré Chang CX, Rodríguez Viera R, Dupuy Nuñez JC. Clinical laboratory studies for the detection of chronic renal disease in population risk groups. MEDISAN [Internet]. 2016 Jan. 14 [cited 2025 Jun. 2];20(1). Available from: https://medisan.sld.cu/index.php/san/article/view/645

Issue

Vol. 20 No. 1 (2016): MEDISAN

Section

Original Articles

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