Diabetes mellitus and periodontal disease: current pathophysiological aspects of their relationship

Authors

  • Martha Elena Fajardo Puig Facultad de Estomatología, Universidad de Ciencias Médicas, Santiago de Cuba
  • Oscar Rodríguez Reyes Facultad de Estomatología, Universidad de Ciencias Médicas, Santiago de Cuba
  • Margarita Hernández Cunill Facultad de Estomatología, Universidad de Ciencias Médicas, Santiago de Cuba
  • Natacha Mora Pacheco Facultad de Estomatología, Universidad de Ciencias Médicas, Santiago de Cuba

Keywords:

diabetes mellitus, periodontal disease, pathophysiological aspects, oral microflora, vascular changes.

Abstract

Diabetes mellitus constitutes a risk factor of periodontal disease.  Also the severity and extension of the periodontal damage is directly related to the diabetes mellitus control in those who suffer from it.  In fact, the prevention of the periodontal disorders in the diabetic patient is the best treatment available at the present time; so that the knowledge and the permanent updating of the pathophysiological aspects in the correlation of both entities, are important to select and to carry out an early and appropriate therapy, not only to reduce the morbidity of the local infection, but also to influence indirectly in the general health.  Taking into consideration these arguments, it was decided to make a comment on the topic.

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Author Biography

Martha Elena Fajardo Puig, Facultad de Estomatología, Universidad de Ciencias Médicas, Santiago de Cuba

Especialista de Segundo Grado en Fisiología Normal y Patológica. Máster en Atención de Urgencias Estomatológicas. Profesor Auxiliar. Investigador Agregado. Departamento de Ciencias Básicas Biomédicas. Facultad de Estomatología. UCM-SC

References

1. Löe H. Periodontal disease: The sixth complication of diabetes mellitus. Diabetes Care. 1993; 16(1): 329-34.

2. Tervonen T, Karjalainen K. Pe¬riodontal disease related to dia¬betic status. A pilot study of the response to periodontal therapy in type 1 diabetes. J Clin Perio¬dontol. 1997; 24(7): 505-10.

3. Promsudthi A, Pimapansri S, Deerochanawong C, Kancha¬navasita W. The effect of pe¬riodontal therapy on uncontro¬lled type 2 diabetes mellitus in older subjects. Oral Dis. 2005; 11(5): 293-8.

4. Herrera D, Rodríguez Casanovas HJ, Herrera Pombo JL. Diabetes y enfermedades periodontales. Madrid: SEPA/Fundación SED; [s. a.] [citado 26 Ene 2016]. Disponible en: http://www.sepa.es/images/stories/SEPA/ESTAR_al_DIA/DIABETES/Dossier_DIABETES.pdf

5. Chen L, Wei B, Li J, Liu F, Xuan D, Xie B, et al. Association of periodontal parameters with metabolic level and systemic inflammatory markers in patients with type 2 diabetes. J Periodontol. 2010; 81(3): 364-71.

6. Saremi A, Nelson RG, Tulloch-Reid M, Hanson RL, Sievers ML, Taylor GW, et al. Periodontal disease and mortality in type 2 diabetes. Diabetes Care 2005; 28(1): 27-32.

7. Bascones Martínez A, Figuero Ruiz E. Periodontal diseases as bacterial infection. Med Oral Patol Oral Cir Bucal. 2004; 9(Suppl.): 92-100.

8. Moore PA. The diabetes-oral health connection. Compend Contin Educ Dent. 2002; 23(12 Suppl): 14-20.

9. Duque de Estrada Riverón J, Rodríguez Calzadilla A. Factores de riesgo en la predicción de las principales enfermedades bucales. Rev Cubana Estomatol. 2001 [citado 30 Ene 2016]; 38(2): 111-9. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75072001000200004]

10. Díaz Romero RM, Villegas Álvarez F. Diabetes e infección periodontal. Rev Nacional de Odontología. 2010 [citado 24 Feb 2016]; 2(7). Disponible en: http://www.intramed.net/contenidover.asp?contenidoID=72517

11. Arrieta Blanco JJ, Bartolomé Villar B, Jiménez Martínez E, Saavedra Vallejo P, Arrieta Blanco FJ. Problemas bucodentales en pacientes con diabetes mellitus (II): Índice gingival y enfermedad periodontal. Med Oral. 2003 [citado 24 Feb 2016]; 8(4): 233-47. Disponible en: http://www.medicinaoral.com/medoralfree/v8i4/medoralv8i4p233.pdf

12. Spiteller G. Is lipid peroxidation of polyunsaturated acids the only source of free radicals that induce aging and age-related diseases? Rejuvenation Res. 2010; 13(1): 91-103.

13. Inchingolo F, Marrelli M, Annibali S, Cristalli MP, Dipalma G, Inchingolo AD, et al. Influence of endodontic treatment on systemic oxidative stress. Int J Med Sci. 2014; 11(1): 1–6.

14. Shao D, Oka SI, Brady CD, Haendeler J, Eaton P, Sadoshima J. Redox modification of cell signaling in the cardiovascular system. J Mol Cell Cardiol. 2012; 52(3): 550-8.

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Published

2016-06-08

How to Cite

1.
Fajardo Puig ME, Rodríguez Reyes O, Hernández Cunill M, Mora Pacheco N. Diabetes mellitus and periodontal disease: current pathophysiological aspects of their relationship. MEDISAN [Internet]. 2016 Jun. 8 [cited 2025 Jun. 2];20(6). Available from: https://medisan.sld.cu/index.php/san/article/view/745

Issue

Vol. 20 No. 6 (2016): MEDISAN

Section

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