Cardiovascular risk factors associated with the mortality of elderly with COVID-19

Authors

Keywords:

COVID-19, cardiovascular risk factors, elderly, mortality.

Abstract

Introduction: The COVID-19 has affected in a disproportionate way the elderly who have a more unfavorable clinical course. 

Objective: To analyze the cardiovascular risk factors associated with the mortality of elderly with COVID-19. 

Methods: An analytic, case-control type study, of 25 elderly belonging to the Ramón López Peña Teaching Polyclinic was carried out in Santiago de Cuba, they died due to COVID 19 between January, 2020 and the same month in 2022 (cases) and  50 that didn't die (controls). The ratio of crossed products, confidence interval and attributable risk in exposed percentage were determined. 

Results: The age was the risk marker of more association and hypertension was the associated disease of more relevance, for a ratio of crossed products 6.0 and 10.1, respectively. 

Conclusions: The findings demonstrated that the patients of advanced age, hypertense, smokers, obese and with cognitive deterioration should be identified, as well as to use a preventive approach that allows the early diagnosis and treatment, to avoid this way fatal outcomes due to COVID-19.   

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References

1. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020 [citado 13/01/2022];382(18):1708-20. Disponible en: https://pubmed.ncbi.nlm.nih.gov/32109013/

2. Hierrezuelo N, González P, León A, Cordero F. Caracterización clínico-epidemiológica de pacientes con la COVID-19 en el policlínico Ramón López Peña. Rev. cuba. hig. epidemiol. 2021 [citado 09/02/2022];58. Disponible en: http://www.revepidemiologia.sld.cu/index.php/hie/article/view/1117

3. Silverio A, Di Maio M, Citro R, Esposito L, Iuliano G, Bellino M, et al. Cardiovascular risk factors and mortality in hospitalized patients with COVID-19: systematic review and meta-analysis of 45 studies and 18,300 patients. BMC Cardiovasc Disord. 2021 [citado 08/01/2022];21(1). Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789083/

4. Hernández DR, González MA, Romo DK, Lima R, Hernández IA, Lumbreras M et al. Increased Risk of Hospitalization and Death in Patients with COVID-19 and Pre-existing Noncommunicable Diseases and Modifiable Risk Factors in Mexico. Arch Med Res. 2020 [citado 05/01/2022];51(7):683-9. Disponible en: https://pubmed.ncbi.nlm.nih.gov/32747155/

5. Yanyan W, Li H, Zhang Z, Liang W, Zhang T, Tong Z, et al. Risk factors for mortality of coronavirus disease 2019 (COVID-19) patients during the early outbreak of COVID-19: a systematic review and meta-analysis. Ann Palliat Med. 2021 [citado 05/01/2022];10(5)5069-83. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33894729/

6. Sabatino J, De Rosa S, Di Salvo G, Indolfi
C. Impact of cardiovascular risk profile on COVID-19 outcome. A meta-analysis. PLoS One. 2020 [citado 05/01/2022];15(8). Disponible en: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0237131

7. EUROPA PRESS. Factores de riesgo cardiovascular, asociados a complicaciones por la COVID-19, 2020 [citado 09/02/2022]. Disponible en: https://www.infosalus.com/salud-investigacion/noticia-factores-riesgo-cardiovascular-asociados-complicaciones-covid-19-20200817075434.html

8. Xu J, Yang X, Yang L, Zou X, Wang Y, Wu Y, et al. Clinical course and predictors of 60-day mortality in 239 critically ill patients with COVID-19: A multicenter retrospective study from Wuhan, China. Crit Care. 2020 [citado 24/01/2022]; 24(1). Disponible en: https://ccforum.biomedcentral.com/articles/10.1186/s13054-020-03098-9

9. González Tabares R, Acosta González FA. Oliva Villa E, Rodríguez Reyes S, Cabeza Echevarría I. Predictores de mal pronóstico en pacientes con la COVID-19. Rev. cuban. med. mil. 2020 [citado 12/02/2022]; 49(4). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-65572020000400020

10. Caramelo F, Ferreira N, Oliveiros B. Estimation of risk factors for COVID-19 mortality – preliminary results. MedRxiv. 2020 [ citado 04/01/2022]. Disponible en: https://www.medrxiv.org/content/10.1101/2020.02.24.20027268v1.full.pdf

11. Más S. Covid-19 y demografía: claves de una pandemia, 2021 [citado 06/02/2022]. Disponible en: https://rebelion.org/covid-19-y-demografia-claves-de-una-pandemia/

12. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020 [citado 04/02/2022];395(10229):1054-62. Disponible en: https://pubmed.ncbi.nlm.nih.gov/32171076/

13. Solano MA, Coronado AR, Salazar J, Sánchez S, Luria DJ, Ordaz WA et al. Factores de riesgo asociados a la mortalidad en pacientes con COVID-19, en el estado de Oaxaca. Avan Cien Sal Med. 2020 [citado 24/01/2022];7(4):99-110. Disponible en: https://www.imbiomed.com.mx/articulo.php?id=115352

14. Shahriar Z, Habboushe J. Critical Review: Preliminary indicators of mortality in subjects infected with COVID-19 based on data from China and South Korea, 2020 [citado 07/01/2022]. Disponible en: https://www.thennt.com/nnt/preliminary-indicators-mortality-subjects-infected-covid-19-based-data-china-south-korea/

15. Cuba. Ministerio de Salud Pública. Dirección Nacional de Registros Médicos y Estadísticas de Salud. Anuario Estadístico de Salud, 2021 [citado 26/05/2022]. Disponible en: https://files.sld.cu/bvscuba/files/2021/08/Anuario-Estadistico-Espa%C3%B1ol-2020-Definitivo.pdf

16. Underner M, Peiffer G, Perriot J, Jaafari N. Tabagisme et maladie à coronavirus 2019 (COVID-19). Rev Mal Respir. 2020 [citado 09/01/2022];37(5):433-6. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141481/

17. Campos Vera NA, Real Cancio RM, Rivas Estany E. Factores de riesgo cardiovasculares, diabetes y COVID-19. Rev. cuba. cardiol. cir. cardiovasc. 2021 [citado 07/02/2022];27(4). Disponible en: http://revcardiologia.sld.cu/index.php/revcardiologia/article/view/1100/pdf

18. Gutiérrez Rodríguez J, Montero Muñoz J, Jiménez Muela F, Guirola García Prendes C, Martínez Rivera M, Gómez Armas L. Variables asociadas con mortalidad en una población de pacientes mayores de 80 años y con algún grado de dependencia funcional, hospitalizados por COVID-19 en un Servicio de Geriatría. Rev Esp Geriatr Gerontol. 2020 [citado 08/02/2022]; 55(6): 317-25. Disponible en: https://www.elsevier.es/es-revista-revista-espanola-geriatria-gerontologia-124-pdf-S0211139X20301098

19. Organización Mundial de la Salud. Informe mundial sobre el envejecimiento y la salud, 2015 [citado 11/02/2022]. Disponible en: https://apps.who.int/iris/bitstream/handle/10665/186463/9789240694811_eng.pdf?sequence=1

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Published

2022-06-20

How to Cite

1.
Hierrezuelo Rojas N, Durruty Medina LE, Magdariaga AH, Gonzales EG, Catellano Hardy T. Cardiovascular risk factors associated with the mortality of elderly with COVID-19. MEDISAN [Internet]. 2022 Jun. 20 [cited 2025 Jun. 4];26(3):e4083. Available from: https://medisan.sld.cu/index.php/san/article/view/4083

Issue

Vol. 26 No. 3 (2022): MAYO-JUNIO

Section

Original Articles

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