Oral Candidiasis in patients with diabetes mellitus

Authors

  • Gladys Aída Estrada Pereira Hospital Provincial Docente Clinicoquirúrgico “Saturnino Lora Torres”, Santiago de Cuba, Cuba.
  • Maricel Marquez Filiu Universidad de Ciencias Médicas, Facultad de Estomatología, Santiago de Cuba, Cuba.
  • José Manuel Díaz Fernández Hospital Provincial Docente Clinicoquirúrgico “Saturnino Lora Torres”, Santiago de Cuba, Cuba.
  • Liliet Antonia Agüero Despaigne Hospital Provincial Docente Clinicoquirúrgico “Saturnino Lora Torres”, Santiago de Cuba, Cuba.

Keywords:

oral candidiasis, diabetes mellitus, clinical and histopathologic diagnosis, pathogen hyphae, yeast-like cells, secondary health care.

Abstract

A descriptive and cross-sectional study of 75 patients with diabetes mellitus who presented oral candidiasis, treated in the stomatological service of the Specialties Polyclinic of "Saturnino Lora Torres" Teaching Provincial Clinical Surgical Hospital in Santiago de Cuba was carried out, from March, 2013 to the same month in 2015, in order to evaluate the results of the clinical and histopathologic diagnosis of the mentioned affection.  The samples for biopsies were fixed and processed with the classic technique of inclusion in paraffin; they were colored with a special stain of Schiff periodic acid, which confirmed the existence of cellular changes.  There was a prevalence of male sex, the 60 years and over age group; the absence of clinical symptoms, the hard palate and the corner of the mouth as the sites of greater prevalence and the erythematous candidiasis as the most common clinical form.  The presence of pathogen hyphae and yeast-like cells were the most outstanding histopathologic findings. 

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References

1. A-Maskari AY, Al Maskari MY, Al-Sudairy S. Oral manifestations and complications of diabetes mellitus: A review. Sultan Qaboos Univ Med J. 2011; 11(2): 179-86.

2. De Menezes Sousa MG, Lopes Costa AL, Giuseppe Roncalli A. Clinical study of the oral manifestations and related factors in type 2 diabetics patients. Braz J Otorhinolaryngol. 2011; 77(2): 145-52.

3. Aguado JM, Ruiz Camps I, Muñoz P, Mensa J, Almirante B, Vázquez L, et al. Recomendaciones sobre el tratamiento de la candidiasis invasiva y otras infecciones por levadura de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC). Actualización 2011. Enferm Infecc Microbiol Clin. 2011; 29(5): 345-61.

4. Pappas PG, Kauffman CA, Andes D, Benjamin DK Jr, Calandra TF, Edwards JE Jr, et al. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society America. Clin Infect Dis. 2009; 48(5): 503–35.

5. Rojas Morales T, Rubio E, Viera N, Morón Medina A, Meza L. Características clínicas y microscópicas de Candida albicans. MedULA. 2013; 22(1): 6-10.

6. Velasco León EC, Mendiola García A, Pizarro Damasco MI. Candidiasis oral en paciente pediátrico sano. Oral. 2013; 14(44): 956-64.

7. Camara Mattos BS, Alves de Sousa A, CG de Magalhaes ME, André M, Brito R. Candida albicans in patients with oronasal communication and obturator prostheses. Braz Dent J. 2009 [citado 8 Feb 2015]; 20(4). Disponible en: http://www.scielo.br/scielo.php?pid=S0103-64402009000400013&script=sci_arttext

8. Santana JC. Candidiasis de la mucosa bucal. En: Santana JC. Infección por el VIH en el complejo bucal. La Habana: Ciencias Médicas; 2000. p. 73-87.

9. Palacios CP, Gómez LM, Cardona N. Candidiasis mucocutánea: espectro clínico. Rev Asoc Colomb Dermatol. 2011; 19: 239-44.

10. Rodríguez Ortega J, Miranda Tarragó J, Morejón Lugones H, Santana Garay JC. Candidiasis de la mucosa bucal. Revisión bibliográfica. Rev Cubana Estomatol. 2002 [citado 8 Feb 2015]; 39(2). Disponible en: http://www.bvs.sld.cu/revistas/est/vol39_2_02/Est07202.htm

11. Hernández Solís SE, González Ramírez AS, Rueda Gordillo F. Capacidad de adhesión de cepas de Candida albicans aisladas de una población de niños portadores sanos. Rev Odontol Latinoam. 2010; 2(2): 33-7.

12. Paranhos HF, Silva-Lovato CH, de Souza RF, Cruz PC, de Freitas-Pontes KM, Watanabe E, et al. Effect of three methods for cleaning dentures on biofilms formed in vitro on acrylic resin. J Prosthodont. 2009; 18(5): 427-31.

13. De Andrade IM, Cruz PC, Silva-Lovato CH, de Souza RF, Souza-Gugelmin MC, Paranhos H de F. Effect of chlorhexidine on denture biofilm accumulation. J Prosthodont. 2012; 21(1): 2-6.

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Published

2015-11-09

How to Cite

1.
Estrada Pereira GA, Marquez Filiu M, Díaz Fernández JM, Agüero Despaigne LA. Oral Candidiasis in patients with diabetes mellitus. MEDISAN [Internet]. 2015 Nov. 9 [cited 2025 May 23];19(11). Available from: https://medisan.sld.cu/index.php/san/article/view/521

Issue

Vol. 19 No. 11 (2015): Medisan

Section

Original Articles

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