Relación de riesgo entre dislipidemia y COVID-19

Izaida Lis Montero López, Wardy Castillo López, Silvio Niño Escofet, Pedro Enrique Miguel Soca

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Resumen

La presencia de dislipidemia en pacientes con la COVID-19 parece agravar el curso clínico de la enfermedad. En esta revisión bibliográfica se describen los principales mecanismos que las vinculan y sus implicaciones en el tratamiento de los pacientes afectados. Para realizar este trabajo se efectuó una búsqueda bibliográfica en bases de datos, tales como Google académico, SciELO, Annual Reviews y PMC. Los descriptores analizados fueron COVID-19, SARS-CoV-2, dislipidemia, LDL-colesterol, HDL-colesterol, triglicéridos, hipercolesterolemia y lipoproteínas VLDL. Se revisaron preferentemente artículos de revistas arbitradas por pares y disponibles a texto completo, publicados en inglés y español.  A pesar de las controversias, la dislipidemia es un factor de riesgo de pronóstico desfavorable en afectados con la COVID-19 y el tratamiento para los pacientes con esa condición desfavorable mejora dicho pronóstico. 

Palabras clave

COVID-19; SARS-CoV-2; dislipidemia; LDL-colesterol; HDL-colesterol triglicéridos; hipercolesterolemia; lipoproteínas VLDL.

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