Anemia in patients with cancer exposed to chemotherapy

Authors

  • María Cristina Céspedes Quevedo Hospital Oncológico Docente Provincial “Conrado Benítez García”, Santiago de Cuba, Cuba.
  • Yeris Leydis León Barrios Hospital Oncológico Docente Provincial “Conrado Benítez García”, Santiago de Cuba, Cuba.
  • Ana Margarita Vinent Céspedes Clínica Estomatológica “30 de Noviembre”, Santiago de Cuba, Cuba.
  • Raiza Agüero Martén Hospital Oncológico Docente Provincial “Conrado Benítez García”, Santiago de Cuba, Cuba.

Keywords:

anemia, cancer, cytostatic, chemotherapy, oncological hospitals

Abstract

A descriptive and cross-sectional study of 146 patients with cancer assisted in the Chemotherapy Service of "Conrado Benítez García" Teaching Oncological Provincial Hospital in Santiago de Cuba, was carried out from January to June, 2015, aimed at describing the variation of anemias before and after having applied the chemotherapy, according to variables such as age, sex, tumoral localization, degree of anemia and cytostatic agent.  In the series the patients aged 41-60 years (46.5%) and the breast cancer (62.3%) prevailed, and the mean hemoglobin before and after the treatment were 113.08 and 104.77 g/L, respectively.  Before receiving the cytostatic 110 patients (75.6%) suffered from anemia, mainly in the light form (60.0%).  The association between the degrees of anemias and the treatment with platinums was not demonstrated; nevertheless, there was a higher number of patients with anemia after the chemotherapy, mainly in the light degree.

 

Downloads

Download data is not yet available.

References

1. Pérez-Oliva Díaz JF. 15 años de Eritropoyetina Recombinante Humana cubana. Beneficios y retos. Rev Haban Cienc Méd. 2013 [citado 6 Sep 2015]; 12(3). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1729-519X2013000300019

2. Tonia T, Mettler A, Robert N, Schwarzer G, Seidenfeld J, Weingart O, et al. Erythropoietin or darbepoetin for patients with cancer. Cochrane Database of Systematic Reviews. 2012 [citado 7 Ene 2016]; 12. Disponible en: http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003407.pub5/pdf

3. Roca Goderich R, Smith Smith VV, Paz Presilla E, Losada Gómez J, Serret Rodríguez B, Llamos Sierra N, et al. Temas de Medicina Interna. 4 ed. La Habana: Editorial Ciencias Médicas; 2002. p. 318-320.

4. Alfonso Orta I, Alonso Carbonell L, Alonso Galván P, Broche Villareal L, Calvo Barbados DM, Cruz Barrios MA, et al. Formulario Nacional de Medicamentos. La Habana: Editorial Ciencias Médicas; 2014.

5. Mendoza Hernández I, Cachimaille Benavides Y, Guerra Chaviano PP, Robaina García M, Damaso Fernández J, Wilford de León M, et al. Impacto en la asistencia médica cubana de la extensión nacional del ior® LeukoCIM a través de ensayos clínicos. Rev Cubana Farm. 2010 [citado 10 Ago 2015]; 44(Sup. 2). Disponible en: http://bvs.sld.cu/revistas/far/vol44_sup2_10/Impacto%20en%20la%20asistencia%20medica%20cubana%20de%20la%20extension%20nacional%20del%20ior%20LeukoCIM%20a%20traves%20de%20EC.pdf

6. Kleinman L, Benjamin K, Viswanathan H, Mattera MS, Bosserman L, Blayney DW, et al. The anemia impact measure (AIM): development and content validation of a patient-reported outcome measure of anemia symptoms and symptom impacts in cancer patients receiving chemotherapy. Qual Life Res. 2012; 21: 1255-66.

7. Flores Balcázar C, Rosales Pérez S, Galván Salazar G, López Navarro O. Anemia inducida por quimioterapia en pacientes oncológicos: papel de los agentes eritropoyéticos. Arch Med. 2015 [citado 7 Jul 2015]; 11(1). Disponible en: http://www.archivosdemedicina.com/medicina-de-familia/anemia-inducida-por-quimioterapia-en-pacientes-oncolgicos-papel-de-los-agentes-eritropoyticos.pdf

8. Aerts J, Swieboda Sadlej A, Karanikiotis C, Labourey JL, Galid A, Wheeler T, et al. Use of darbepoetin alfa in European clinical practice for the management of chemotherapy-induced anaemia in four tumour types: final data from the CHOICE study. Curr Med Res Opin. 2012; 28(7): 1089-99.

9. Bittner N, Cipkova A, Móciková H, Wojciechowska-Lampka E, Balázs M, Ocvirk J, et al. Current management of chemotherapy –induced anemia with darbepoetin alfa– the Apriori study. J Clin Oncol. 2011; 29(Supl.): 19723.

10. Cuba. Ministerio de Salud Pública. Dirección Nacional de Registro Médicos y Estadísticos de Salud. Anuario Estadístico de Salud 2015. La Habana: MINSAP; 2016 [citado 25 Abril 2016]. Disponible en: http://files.sld.cu/dne/files/2016/04/Anuario_2015_electronico-1.pdf

11. Suardíaz Pareras J, Cruz Rodríguez C, Colina Rodríguez A. Laboratorio clínico. La Habana: Editorial Ciencias Médicas; 2004.

12. Ohashi Y, Uemura Y, Fujisaka Y, Sugiyama T, Ohmatsu H, Katsumata N, et al. Meta-analysis of epoetin beta and darbepoetin alfa treatment for chemotherapy-induced anemia and mortality: Individual patient data from Japanese randomized, placebo-controlled trials. Cancer Sci. 2013; 104(4): 481-5.

Downloads

Published

2016-08-11

How to Cite

1.
Céspedes Quevedo MC, León Barrios YL, Vinent Céspedes AM, Agüero Martén R. Anemia in patients with cancer exposed to chemotherapy. MEDISAN [Internet]. 2016 Aug. 11 [cited 2025 Jul. 13];20(8). Available from: https://medisan.sld.cu/index.php/san/article/view/1017

Issue

Vol. 20 No. 8 (2016): MEDISAN

Section

Original Articles

License

All the articles can be downloaded or read for free. The journal does not charge any amount of money to the authors for the reception, edition or the publication of the articles, making the whole process completely free. Medisan has no embargo period and it is published under the license of Creative Commons, International Non Commercial Recognition 4.0, which authorizes the copy, reproduction and the total or partial distribution of the articles in any format or platform, with the conditions of citing the source of information and not to be used for profitable purposes.

Similar Articles

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 > >> 

You may also start an advanced similarity search for this article.